I had some problems with dependencies from winehq ( missing libX11, libxml2, … )
For windows games ( 32bit and 64bits ) I suggest than during the installating of Lutris to install a separate winehq-staging installation.
Lutris can be use as usual but avoid all problems from winehq.
my initial problem :
World of Tanks missing wotlauncher.exe [solved]
to solve it (for debian stretch) :
dpkg –add-architecture i386
wget -q -O - wget https://dl.winehq.org/wine-builds/Release.key | apt-key add -
echo ‘deb http://dl.winehq.org/wine-builds/debian/ stretch main contrib non-free’ > /etc/apt/source.list
apt install winehq-staging
source : wine dependency