(Solved)Suddenly WoW became unplayable after reboot

EDIT: Solved

I can log into my Character just fine, but i have neither sound nor does any keybind work. Trying multiple Wine Versions and fresh installing the Prefix and Battle.net (WoW is stored outside prefix) didnt helped out

lutris -d output with game debug active
https://gist.githubusercontent.com/ninelore/15f018f537329752517feb45f45d8a12/raw/b431d8598e13341158e9ee5f7550ca0dc5110fb8/lutris-wow-issue-20200625