I suggest not using DXVK to play the game. It’s not necessary to run and it doesn’t offer big improvements. I also doubt the game runs based on DXVK, but you can test with DXVK 0.80 to see if your problem is magically solved. Trying to toggle these enhancements off and on back again is a good way to start debugging it yourself.
The game had a new update just two days ago and it requires reinstalling the game, as far as I know, because the patcher doesn’t work properly on Wine at the moment.
Thank you both for your advice. Here is an update.
After disabling DXVK the game started. Of course, there are updates to download. This is a taxing process because it often crashes during this part. That much is known, but you reload it and eventually it downloads.
Try checking the System Option “run in single core”. I found that it helped me patch these last two files in some occasions. When I needed to reinstall the game (after every new patch), starting with “run in single core” was more harmful then helpful, but it surely helps if the last two files don’t finish up.