On archlinux, Path Of Exile is missing lots of fonts ( or null/ failure to get handles to the fonts resources ) so the game runs, but most of the UI/Buttons are blank (no text) ( especially the Ambre-colored/skinned buttons ) .
I installed on /usr/share/fonts also on ~/.fonts, all of the windows fonts I have on my windows 10 system.
I put them (the fonts files) also on […]/Games/path-of-exile/drive_c/windows/Fonts/
Thank you 
Hi Bretzelus,
I don’t play PoE nor am I an expert in Arch, but I want to try to help you anyway.
Did you install ttf-ms-fonts from the AUR?
I assume that you use WineHQ to play the game… Did you follow Glorious Eggroll’s guide on escaping the
Dependency Hell? How to get out of Wine Dependency hell
And there seems to be a topic in the Arch-Forum, which might relate to your problem. Maybe you want to have a look there as well, if my previous tipps didn’t work. Fontconfig related problem after last update
I hope this will help you.
Best regards
zummsel