Is there a way to trick Masseffect into not using 3DNow
Take a read though https://www.reddit.com/r/masseffect/comments/7omtl1/no_spoilers_any_suggestions_on_fixing_this/ and see if any of the suggestions help.
As I don’t have an AMD APU I cannot attest if they will or won’t work for you.
I tried that mod before but couldn’t get it to work. I was wondering if it needs a wine dll override