Lutris doesnt start - Fresh install

I have a fresh Linux install but Lutris doesnt start.

[andre@flammensturm ~]$ lutris --submit-issue
2021-09-13 22:13:49,951: Magic not available. Unable to automatically find game executables. Please install python-magic
2021-09-13 22:13:49,979: Loading of DXVK versions failed, defaulting to locally available versions
2021-09-13 22:13:49,996: Loading of DXVK versions failed, defaulting to locally available versions
2021-09-13 22:13:50,022: No cores found
2021-09-13 22:13:50,094: Initializing lutris
2021-09-13 22:13:50,097: Loading of DXVK versions failed, defaulting to locally available versions
2021-09-13 22:13:50,119: Loading of DXVK versions failed, defaulting to locally available versions
2021-09-13 22:13:50,478: Runtime gamecontrollerdb is not available locally
2021-09-13 22:13:50,480: Runtime dumbxinputemu is not available locally
2021-09-13 22:13:50,480: Runtime x360ce is not available locally
2021-09-13 22:13:50,481: Runtime p7zip is not available locally
2021-09-13 22:13:50,492: Runtime lib64 is not available locally
2021-09-13 22:13:50,495: Runtime lib32 is not available locally
2021-09-13 22:13:50,498: Runtime winetricks is not available locally
2021-09-13 22:13:50,502: Runtime Ubuntu-18.04-i686 is not available locally
2021-09-13 22:13:50,503: Runtime Ubuntu-18.04-x86_64 is not available locally

Hope, anyone can help.

What distro are you using and how did you install Lutris?