After first runs(1500mb update), client killing itself.
DEBUG 2018-08-12 03:58:26,407 [thread]:Running command: "/home/myusername/.local/share/lutris/runners/wine/lol-3.13-x86_64/bin/wine" "/home/myusername/Games/league-of-legends/drive_c/Riot Games/League of Legends/LeagueClient.exe"
DEBUG 2018-08-12 03:58:26,407 [thread]:Storing environment variable SDL_VIDEO_FULLSCREEN_DISPLAY to off
DEBUG 2018-08-12 03:58:26,407 [thread]:Storing environment variable MESA_GLTHREAD to true
DEBUG 2018-08-12 03:58:26,407 [thread]:Storing environment variable __GL_THREADED_OPTIMIZATIONS to 1
DEBUG 2018-08-12 03:58:26,407 [thread]:Storing environment variable DRI_PRIME to 0
DEBUG 2018-08-12 03:58:26,408 [thread]:Storing environment variable STEAM_RUNTIME to /home/myusername/.local/share/lutris/runtime/steam
DEBUG 2018-08-12 03:58:26,408 [thread]:Storing environment variable LD_LIBRARY_PATH to /usr/lib:/usr/lib32:/home/myusername/.local/share/lutris/runtime/lib32:/home/myusername/.local/share/lutris/runtime/steam/i386/lib/i386-linux-gnu:/home/myusername/.local/share/lutris/runtime/steam/i386/lib:/home/myusername/.local/share/lutris/runtime/steam/i386/usr/lib/i386-linux-gnu:/home/myusername/.local/share/lutris/runtime/steam/i386/usr/lib:/home/myusername/.local/share/lutris/runtime/lib64:/home/myusername/.local/share/lutris/runtime/steam/amd64/lib/x86_64-linux-gnu:/home/myusername/.local/share/lutris/runtime/steam/amd64/lib:/home/myusername/.local/share/lutris/runtime/steam/amd64/usr/lib/x86_64-linux-gnu:/home/myusername/.local/share/lutris/runtime/steam/amd64/usr/lib:$LD_LIBRARY_PATH
DEBUG 2018-08-12 03:58:26,408 [thread]:Storing environment variable WINEDEBUG to -all
DEBUG 2018-08-12 03:58:26,408 [thread]:Storing environment variable WINEARCH to win64
DEBUG 2018-08-12 03:58:26,408 [thread]:Storing environment variable WINE to /home/myusername/.local/share/lutris/runners/wine/lol-3.13-x86_64/bin/wine
DEBUG 2018-08-12 03:58:26,409 [thread]:Storing environment variable WINEPREFIX to /home/myusername/Games/league-of-legends
LeagueClient.exe(00000009): ALWAYS| Application Version:8.15.240.2334 - CL:2402334 - Build Date:Jul 31 2018 - Build Time:11:13:33
DEBUG 2018-08-12 03:58:28,608 [thread]:Start process monitoring
DEBUG 2018-08-12 03:58:28,608 [thread]:Processes monitored: LeagueClient.ex (14945:Z), LeagueClientUx. (15031:S), LeagueClient.ex (14986:R)
DEBUG 2018-08-12 03:58:28,609 [thread]:Processes excluded: wineserver (14948:S)
DEBUG 2018-08-12 03:58:30,547 [thread]:Processes monitored: LeagueClient.ex (14945:Z), LeagueClient.ex (14986:S)
DEBUG 2018-08-12 03:58:32,533 [thread]:Processes monitored: LeagueClient.ex (14945:Z)
DEBUG 2018-08-12 03:58:34,545 [thread]:Waiting for processes to exit
DEBUG 2018-08-12 03:58:34,545 [thread]:Thread is no longer running
DEBUG 2018-08-12 03:58:34,545 [thread]:Restoring environment
DEBUG 2018-08-12 03:58:36,410 [game]:Game thread stopped
DEBUG 2018-08-12 03:58:36,410 [game]:Game thread still running, stopping it (state: running)
DEBUG 2018-08-12 03:58:36,411 [game]:League of Legends stopped at Sun, 12 Aug 2018 03:58:36
DEBUG 2018-08-12 03:58:36,527 [wine]:Killing all wine processes: ['/home/myusername/.local/share/lutris/runners/wine/lol-3.13-x86_64/bin/wineserver', '-k']
DEBUG 2018-08-12 03:58:36,527 [wine]: Wine prefix: /home/myusername/Games/league-of-legends
DEBUG 2018-08-12 03:58:36,527 [wine]: Wine arch: win64
DEBUG 2018-08-12 03:58:36,532 [wine]:Waiting for wine processes to terminate
DEBUG 2018-08-12 03:58:36,532 [thread]:Restoring environment
DEBUG 2018-08-12 03:58:36,532 [thread]:Killing all remaining processes
Thanks…
EDIT: https://www.gloriouseggroll.tv/how-to-get-out-of-wine-dependency-hell/ helped.