GOG Bioshock Infinite complete edition freezes

I purchased Bioshock Infinite complete edition from GOG. Despite it is marked to run stable via lutris/wine, I was not able to solve the freeze-problem. To the best of my knowledge, here

https://www.pcgamingwiki.com/wiki/BioShock_Infinite

the most complete problem solving list is provided. After all my try and error the last days, I switched off the intro videos, the game starts, it is possible to change some settings in the game own menu, but then it freezes. To my opinion, it is a CPU-related problem, which is not fixed by developers. I did not find any lutris or wine description on how to run an EXE using only a single core.

my specifications:
Ubuntu 20.04.1 LTS (64 Bit)
Intel® Core™ i7-4770K CPU @ 3.50GHz
Nvidia GeForce RTX 2080
RAM: 32058 MB

In the game’s options in Lutris, go to the System options tab and tick Show advanced options at the bottom of the window. This will reveal the option to Restrict to single core as shown here: