I purchased Bioshock Infinite complete edition from GOG. Despite it is marked to run stable via lutris/wine, I was not able to solve the freeze-problem. To the best of my knowledge, here
the most complete problem solving list is provided. After all my try and error the last days, I switched off the intro videos, the game starts, it is possible to change some settings in the game own menu, but then it freezes. To my opinion, it is a CPU-related problem, which is not fixed by developers. I did not find any lutris or wine description on how to run an EXE using only a single core.
Ubuntu 20.04.1 LTS (64 Bit)
Intel® Core™ i7-4770K CPU @ 3.50GHz
Nvidia GeForce RTX 2080
RAM: 32058 MB