Hello,
In the idea to share my experience,
The game is smooth on Radeon RX 5600 XT driver version 5.6.5.20.30 with the following settings:
Runner: wine
Architecture: x64
Wine version: proton-5.11-GE-3-MF or proton-5-9-GE-5-ST
Winetricks: off
Enable DXVK: on
DXVK vers: 1.7
Esync: on
Windowed: on <<< very important
virtual desktop resolution: 1920x1080
ACO shader compiler: off (color issue with on)
Others settings on default
Performances:
Settings in game: High
FPS vsync on @ 60 in desert and 40 in city.
The version of my game is 1.2 from fitgirl.